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In critically ill children, fluid overload is consistently associated with worse outcomes
- Source :
- BMJ evidence-based medicine. 24(1)
- Publication Year :
- 2018
-
Abstract
- Commentary on: Alobaidi R, Morgan C, Basu RK, et al . Association between fluid balance and outcomes in critically ill children: a systematic review and meta-analysis. JAMA Pediatr. 2018;172(3):257–268. Early goal-directed fluid resuscitation is the foundation of paediatric clinical practice parameters for septic shock and hypovolaemic shock management.1 Moderating fluid resuscitation is the observation that fluid overloaded children have higher mortality rates and longer lengths of stay.2 The Fluid Expansion as Supportive Therapy randomised controlled trial found African children with febrile illness and impaired perfusion who received fluid bolus therapy had a higher mortality rate than those who received no bolus therapy. However, it was conducted in hospitals without intensive care units and therefore does not generalise to high resource states.3 This systematic review and meta-analysis examines the measure and definition of fluid overload and its association with …
- Subjects :
- medicine.medical_specialty
Resuscitation
business.industry
Septic shock
Mortality rate
Critical Illness
MEDLINE
Water-Electrolyte Imbalance
General Medicine
Water-Electrolyte Balance
medicine.disease
law.invention
Bolus (medicine)
Randomized controlled trial
law
Supportive psychotherapy
Intensive care
medicine
Humans
Intensive care medicine
business
Child
Original Investigation
Subjects
Details
- ISSN :
- 25154478
- Volume :
- 24
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMJ evidence-based medicine
- Accession number :
- edsair.doi.dedup.....ab23291157b148453a0f7cc168edf8f9