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Modified Glasgow Prognostic Score 2 as a Prognostic Marker in Patients With Metastatic Urothelial Carcinoma
- Source :
- In Vivo
- Publication Year :
- 2021
- Publisher :
- Anticancer Research USA Inc., 2021.
-
Abstract
- Background/Aim: Predicting the prognosis of metastatic urothelial carcinoma (mUC) patients is needed for clinical decisions. We examined the value of a modified Glasgow prognostic score (mGPS) as a predictive marker for mUC patients. Patients and Methods: In a multicenter study, 68 mUC patients received short hydration gemcitabine/ cisplatin (shGC) and 74 received pembrolizumab (PEM). Patients were allocated according to mGPS. Progression-free (PFS) and cancer-specific (CSS) survival were examined. Results: Higher mGPS reflected poorer PFS and CSS in shGC (p=0.03, p
- Subjects :
- Pharmacology
Cisplatin
Carcinoma, Transitional Cell
Cancer Research
medicine.medical_specialty
Metastatic Urothelial Carcinoma
Predictive marker
business.industry
Pembrolizumab
Prognosis
Gastroenterology
General Biochemistry, Genetics and Molecular Biology
Gemcitabine
Prognostic score
Urinary Bladder Neoplasms
Internal medicine
Humans
Medicine
Biomarker (medicine)
Risk factor
business
Retrospective Studies
Research Article
medicine.drug
Subjects
Details
- ISSN :
- 17917549 and 0258851X
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- In Vivo
- Accession number :
- edsair.doi.dedup.....ab5bc122dc6cfe357f6c59fae5410350
- Full Text :
- https://doi.org/10.21873/invivo.12565