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A CRISPR edit for heart disease
- Source :
- Nature. 555:S23-S25
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- A one-off injection to reduce the risk of cardiovascular disease is now a prospect thanks to advances in gene editing. A one-off injection to reduce the risk of cardiovascular disease is now a prospect thanks to advances in gene editing.
- Subjects :
- 0301 basic medicine
Heart Diseases
Heart disease
Genetic enhancement
Hypercholesterolemia
Myocardial Ischemia
Disease
030204 cardiovascular system & hematology
Antibodies, Monoclonal, Humanized
Bioinformatics
Dystrophin
Mice
03 medical and health sciences
0302 clinical medicine
Genome editing
Animals
Humans
Medicine
CRISPR
Muscular dystrophy
Apolipoproteins C
Angiopoietin-Like Protein 3
Gene Editing
Multidisciplinary
business.industry
PCSK9 Inhibitors
Antibodies, Monoclonal
Cholesterol, LDL
Genetic Therapy
medicine.disease
Muscular Dystrophy, Duchenne
Stroke
Disease Models, Animal
Angiopoietin-like Proteins
030104 developmental biology
Amino Acid Substitution
Apolipoprotein B-100
Mutation
Monoclonal
Mutation (genetic algorithm)
Patient Safety
CRISPR-Cas Systems
Proprotein Convertase 9
business
Lipoprotein(a)
Subjects
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 555
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi.dedup.....ab60f8436671e49e0214b3f26fb9a4ef