Stereodefined Homopropargyl Amines by Tandem Nucleophilic Addition/Fragmentation of Dihydropyridone Triflates

Authors :: Gregory B. Dudley
Jumreang Tummatorn
Source :: Organic Letters. 13:158-160
Publication Year :: 2010
Publisher :: American Chemical Society (ACS), 2010.
Abstract: Dihydropyridone (DHPD) triflates undergo nucleophile-triggered fragmentation to provide homopropargyl amine derivatives, the stereochemistry of which is defined by starting from readily available β-amino esters.

Subjects :: Nucleophilic addition
Tandem
Fragmentation (mass spectrometry)
Chemistry
Organic Chemistry
Organic chemistry
Physical and Theoretical Chemistry
Biochemistry
Amine derivatives

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