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Aryliodoazide Synthons: A Different Approach for Diversified Synthesis of 2-Aminothiazole, 1,3-Thiazole, and 1,3-Selenazole Scaffolds
- Source :
- ACS combinatorial science. 21(7)
- Publication Year :
- 2019
-
Abstract
- Several straightforward and practical processes have been established for the construction of 2-aminothiazoles, 1,3-thiazoles and 1,3-selenazoles from aryliodoazides. These strategies successfully proceed with a wide spectrum of substituted thioamides and its derivatives producing the resulting five-membered heterocycles obtained in satisfactory yields. The unique features of these protocols are operational simplicity and highly functional group tolerance, which make them convenient and practical routes for the preparation of various libraries of 2-aminothiazoles, 1,3-thiazoles, and 1,3-selenazoles.
- Subjects :
- chemistry.chemical_classification
Azoles
Azides
Molecular Structure
010405 organic chemistry
media_common.quotation_subject
Synthon
2-aminothiazole
General Chemistry
General Medicine
010402 general chemistry
01 natural sciences
Combinatorial chemistry
0104 chemical sciences
chemistry.chemical_compound
Thiazoles
chemistry
Organoselenium Compounds
Functional group
Combinatorial Chemistry Techniques
Simplicity
Hydrocarbons, Iodinated
Thiazole
Thioamide
media_common
Subjects
Details
- ISSN :
- 21568944
- Volume :
- 21
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- ACS combinatorial science
- Accession number :
- edsair.doi.dedup.....abc9998a7eb72233dc26eecaba820b68