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Assessment of left ventricular deformation in patients with type 2 diabetes mellitus by cardiac magnetic resonance tissue tracking
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group, 2020.
-
Abstract
- To quantify the global and regional left ventricular (LV) myocardial strain in type 2 diabetes mellitus (T2DM) patients using cardiac magnetic resonance (CMR) tissue-tracking techniques and to determine the ability of myocardial strain parameters to assessment the LV deformation. Our study included 98 adult T2DM patients (preserved LV ejection fraction [LVEF], 72; reduced LVEF, 26) and 35 healthy controls. Conventional LV function, volume-time curve parameters and LV remodeling index were measured using CMR. Global and regional LV myocardial strain parameters were measured using CMR tissue tracking and compared between the different sub-groups. Receiver operating characteristic analysis was used to assess the diagnostic accuracy. Regression analyses were conducted to determine the relationship between strain parameters and the LV remodeling index. The results show that global radial peak strain (PS) and circumferential PS were not significantly different between the preserved-LVEF group and control group (P > 0.05). However, longitudinal PS was significantly lower in the preserved-LVEF group than in the control group (P = 0.005). Multivariate linear and logistic regression analyses showed that global longitudinal PS was independently associated (β = 0.385, P
- Subjects :
- 0301 basic medicine
Cardiac function curve
Adult
Male
medicine.medical_specialty
Tissue tracking
lcsh:Medicine
Logistic regression
Article
03 medical and health sciences
0302 clinical medicine
Diabetes complications
Internal medicine
medicine
Image Processing, Computer-Assisted
Humans
In patient
cardiovascular diseases
lcsh:Science
Multidisciplinary
Ejection fraction
Receiver operating characteristic analysis
Ventricular Remodeling
business.industry
Myocardium
lcsh:R
Type 2 Diabetes Mellitus
Heart
Stroke Volume
Middle Aged
Magnetic Resonance Imaging
030104 developmental biology
Diabetes Mellitus, Type 2
Cardiology
cardiovascular system
Female
lcsh:Q
Cardiac magnetic resonance
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....abeff60e1cb2bd47f6d5af11cf3664b6