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MicroRNAs of Epstein-Barr virus control innate and adaptive anti-viral immunity
- Source :
- J. Virol. 91:e01667-16 (2017)
- Publication Year :
- 2017
- Publisher :
- Amer Soc Microbiology, 2017.
-
Abstract
- Epstein-Barr virus (EBV) has established lifelong infection in more than 90% of humanity. While infection is usually controlled by the immune system, the human host fails to completely eliminate the pathogen. Several herpesviral proteins are known to act as immunoevasins, preventing or reducing recognition of EBV-infected cells. Only recently were microRNAs of EBV identified to reduce immune recognition further. This Gem summarizes what we know about immunomodulatory microRNAs of herpesviruses.
- Subjects :
- 0301 basic medicine
Intrinsic immunity
Herpesvirus 4, Human
Immunology
Biology
medicine.disease_cause
Microbiology
Virus
03 medical and health sciences
Antiviral immunity
0302 clinical medicine
Immune system
Cancer
Human Herpesviruses
Immune Evasion
Immune Surveillance
Microrna
Virology
hemic and lymphatic diseases
microRNA
medicine
Humans
Pathogen
Gem
Epstein–Barr virus
MicroRNAs
Immune recognition
030104 developmental biology
Gene Expression Regulation
030220 oncology & carcinogenesis
Insect Science
Host-Pathogen Interactions
RNA, Viral
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- J. Virol. 91:e01667-16 (2017)
- Accession number :
- edsair.doi.dedup.....ac0a6e69fb3f9a58d1c5e415409963ad