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Clinical and prognostic role of interim 18F-FDG PET/CT in elderly Hodgkin lymphoma: a dual-center experience
- Source :
- Leukemia & Lymphoma. 61:3209-3216
- Publication Year :
- 2020
- Publisher :
- Informa UK Limited, 2020.
-
Abstract
- Hodgkin lymphoma (HL) has a bimodal age distribution curve, with a second peak in people aged more than 60 years. Interim PET/CT (iPET/CT) is highly predictive for PFS and OS in young HL, but it has not been sufficiently studied in the elderly. In this retrospective dual-center study, 82 patients with HL and aged 65 or more who performed iPET/CT were included. At iPET/CT, 60 patients had a complete metabolic response, 18 partial responses, and 4 progressions of disease. Baseline PET/CT metabolic features were not significantly correlated with the metabolic response at interim. In patients with interim complete metabolic response, PFS and OS were significantly longer than in patients without complete response(
- Subjects :
- Cancer Research
elderly
03 medical and health sciences
0302 clinical medicine
Fluorodeoxyglucose F18
immune system diseases
Interim pet ct
Positron Emission Tomography Computed Tomography
hemic and lymphatic diseases
Interim
Humans
Medicine
interim PET/CT
Aged
Retrospective Studies
business.industry
18F-FDG PET/CT
Hematology
Middle Aged
Prognosis
Hodgkin Disease
Interim pet
Hodgkin lymphoma
Oncology
Positron-Emission Tomography
030220 oncology & carcinogenesis
Age distribution
Fdg pet ct
business
Nuclear medicine
030215 immunology
Subjects
Details
- ISSN :
- 10292403 and 10428194
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- Leukemia & Lymphoma
- Accession number :
- edsair.doi.dedup.....ac120ec076348a078ce3cb4c42f08002