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Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s disease patient using self-replicating RNA vector
- Source :
- Stem Cell Research, Vol 50, Iss, Pp 102137-(2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Induced pluripotent stem cell (iPSC) line HUi002-A was reprogrammed from skin fibroblasts via non-integrating, virus free self-replicating RNA. Skin fibroblasts from a 53-year-old male Caucasian, non-familial Parkinson's disease patient, idiopathic (clinical summary confirmed Parkinson's disease) was obtained from the Coriell Institute (AG20442). Generated iPSCs were characterized and pluripotency was confirmed.
- Subjects :
- 0301 basic medicine
Parkinson's disease
RNA
Disease patient
Cell Biology
General Medicine
Disease
Biology
medicine.disease
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
lcsh:Biology (General)
medicine
Cancer research
Vector (molecular biology)
Line (text file)
Virus free
Induced pluripotent stem cell
lcsh:QH301-705.5
030217 neurology & neurosurgery
Developmental Biology
Subjects
Details
- ISSN :
- 18735061
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Stem Cell Research
- Accession number :
- edsair.doi.dedup.....ac17a9f027b13c8423a396a6b70f512c
- Full Text :
- https://doi.org/10.1016/j.scr.2020.102137