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Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s disease patient using self-replicating RNA vector

Authors :
Harry Murti
Sang Hun Lee
Indra Bachtiar
Siska Yuliana Sari
Kelvin Pieknell
Yanuar Alan Sulistio
Source :
Stem Cell Research, Vol 50, Iss, Pp 102137-(2021)
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

Induced pluripotent stem cell (iPSC) line HUi002-A was reprogrammed from skin fibroblasts via non-integrating, virus free self-replicating RNA. Skin fibroblasts from a 53-year-old male Caucasian, non-familial Parkinson's disease patient, idiopathic (clinical summary confirmed Parkinson's disease) was obtained from the Coriell Institute (AG20442). Generated iPSCs were characterized and pluripotency was confirmed.

Details

ISSN :
18735061
Volume :
50
Database :
OpenAIRE
Journal :
Stem Cell Research
Accession number :
edsair.doi.dedup.....ac17a9f027b13c8423a396a6b70f512c
Full Text :
https://doi.org/10.1016/j.scr.2020.102137