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A novel 'turn-on' coumarin-based fluorescence probe with aggregation-induced emission (AIE) for sensitive detection of hydrazine and its imaging in living cells
- Source :
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 222
- Publication Year :
- 2019
-
Abstract
- An aggregation-induced emission (AIE)- and intramolecular charge transfer (ICT)-based probe 1 (7‑hydroxy‑3‑(3‑methyl‑isoxazol‑5‑yl)‑chromen‑2‑one) that is highly selective for N2H4 has been synthesized, exhibiting a ‘turn-on’ response toward N2H4 in CH3CN/H2O solution. The detection limit of the probe was 2.90 ppb, which was evidently lower than the threshold limit value (10 ppb) recommended by the Environmental Protection Agency. Notably, the sensor could be used for the detection of N2H4 in living cells.
- Subjects :
- Models, Molecular
Hydrazine
02 engineering and technology
010402 general chemistry
Photochemistry
01 natural sciences
Analytical Chemistry
Turn (biochemistry)
chemistry.chemical_compound
Coumarins
Humans
Benzopyrans
Aggregation-induced emission
Instrumentation
Spectroscopy
Fluorescent Dyes
Detection limit
Microscopy, Confocal
021001 nanoscience & nanotechnology
Highly selective
Coumarin
Fluorescence
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Hydrazines
Spectrometry, Fluorescence
chemistry
Microscopy, Fluorescence
Intramolecular force
0210 nano-technology
HeLa Cells
Subjects
Details
- ISSN :
- 18733557
- Volume :
- 222
- Database :
- OpenAIRE
- Journal :
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- Accession number :
- edsair.doi.dedup.....ac809ebe8b7db2d45fe7415190cbf6bd