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Problem Based Review: The patient who has taken an overdose of long-acting insulin analogue
- Source :
- Scopus-Elsevier
- Publication Year :
- 2013
- Publisher :
- Rila Publications Ltd, 2013.
-
Abstract
- Insulin overdose can cause harm due to hypoglycaemia, effects on electrolytes and acute hepatic injury. The established long-acting insulin analogue preparations (detemir and glargine) can present specific management problems because, in overdose, their effects are extremely prolonged, often lasting 48-96 hours. The primary treatment is continuous intravenous 10% or 20% glucose infusion with frequent capillary blood glucose monitoring. Surgical excision of the insulin injection site has been used successfully, even days after the overdose occurred. Once the effects of overdose have receded, diabetes treatment must be restarted with care, especially in patients with type 1 diabetes. Monitoring serum insulin concentration has been successfully used to predict when the effects of the overdose will cease.
- Subjects :
- Blood glucose monitoring
Type 1 diabetes
medicine.medical_specialty
medicine.diagnostic_test
Insulin glargine
business.industry
Insulin
medicine.medical_treatment
General Medicine
Critical Care and Intensive Care Medicine
medicine.disease
Drug overdose
Diabetes mellitus
Anesthesia
Blood Glucose Self-Monitoring
Emergency Medicine
Internal Medicine
medicine
Intensive care medicine
business
medicine.drug
Insulin detemir
Subjects
Details
- ISSN :
- 17474884
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Acute Medicine Journal
- Accession number :
- edsair.doi.dedup.....ac851b611626273860ea73e474a8a3f2
- Full Text :
- https://doi.org/10.52964/amja.0312