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Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a meta-analysis
- Source :
- Oncotarget
- Publication Year :
- 2016
- Publisher :
- Impact Journals, LLC, 2016.
-
Abstract
- CD44 is a well-established cancer stem cell marker playing a crucial role in tumor metastasis, recurrence and chemo-resistance. Genetic variants of CD44 have been shown to be associated with susceptibility to various cancers; however, the results are confounding. Hence, we performed a meta-analysis to clarify these associations more accurately. Overall, rs13347 (T vs. C: OR=1.30, p=
- Subjects :
- 0301 basic medicine
Oncology
medicine.medical_specialty
Polymorphism, Single Nucleotide
susceptibility
Metastasis
03 medical and health sciences
0302 clinical medicine
Asian People
Risk Factors
Neoplasms
Internal medicine
Genetic variation
medicine
Humans
cancer
Genetic Predisposition to Disease
single nucleotide polymorphisms (SNP)
CD44
Allele
Polymorphism, Genetic
biology
business.industry
Confounding
Haplotype
Genetic Variation
Cancer
medicine.disease
meta-analysis
Hyaluronan Receptors
030104 developmental biology
030220 oncology & carcinogenesis
Meta-analysis
biology.protein
Clinical Research Paper
business
Subjects
Details
- ISSN :
- 19492553
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Oncotarget
- Accession number :
- edsair.doi.dedup.....aca39710b96644c8ed8e9fb8c0eec017
- Full Text :
- https://doi.org/10.18632/oncotarget.10951