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Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a meta-analysis

Authors :
Yun-Mi Lee
Vishal Chandra
Jong Joo Kim
Usha Gupta
Rajani Rai
Balraj Mittal
Source :
Oncotarget
Publication Year :
2016
Publisher :
Impact Journals, LLC, 2016.

Abstract

CD44 is a well-established cancer stem cell marker playing a crucial role in tumor metastasis, recurrence and chemo-resistance. Genetic variants of CD44 have been shown to be associated with susceptibility to various cancers; however, the results are confounding. Hence, we performed a meta-analysis to clarify these associations more accurately. Overall, rs13347 (T vs. C: OR=1.30, p=

Details

ISSN :
19492553
Volume :
7
Database :
OpenAIRE
Journal :
Oncotarget
Accession number :
edsair.doi.dedup.....aca39710b96644c8ed8e9fb8c0eec017
Full Text :
https://doi.org/10.18632/oncotarget.10951