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Language in young females with fragile X syndrome: Influence on the neurocognitive profile and adaptive behavior
- Source :
- American Journal of Medical Genetics Part A. 185:1448-1460
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Fragile X syndrome (FXS) is the leading cause of inherited intellectual disability. The objective of this research is to analyze the relationship between linguistic functions and performance of the following neuropsychological functions: executive, quantitative reasoning, social perception, behavior, social skills, and adaptive behavior. A neuropsychological and behavioral evaluations were carried out with a group of 26 girls with FXS, and 14 girls without FXS as a control group, using standardized tests. The two groups were homogeneous in age and IQ. Significant differences were found between groups in the relationship between some language processes: inhibition, auditory working memory, cognitive flexibility, level of social adaptation, self-direction, conceptual adaptation, academic skills, leadership ability, theory of mind, and arithmetic. In the group of girls with FXS, it was found that different aspects of language influence some of the executive functions evaluated, in addition to some specific aspects of social perception, adaptive behavior, and quantitative reasoning, in different ways. Future research should incorporate the study of the influence of other cognitive variables such as visual perception and executive function on behavioral, social, and adaptive aspects to know the real influence of all the cognitive variables on the behavior of girls with FXS.
- Subjects :
- Adaptive behavior
Speech-Language Pathology
Adolescent
Social perception
Cognitive flexibility
Cognition
Executive functions
medicine.disease
Developmental psychology
Social Skills
Social Perception
Social skills
Fragile X Syndrome
Intellectual Disability
Adaptation, Psychological
Intellectual disability
Genetics
medicine
Humans
Female
Child
Social Behavior
Psychology
Neurocognitive
Genetics (clinical)
Subjects
Details
- ISSN :
- 15524833 and 15524825
- Volume :
- 185
- Database :
- OpenAIRE
- Journal :
- American Journal of Medical Genetics Part A
- Accession number :
- edsair.doi.dedup.....acda3833b1e0d4ed8ad5021585c921c3