Vigabatrin-induced gingival overgrowth

Authors :: Joshua Shemer
Joseph Katz
Gavriel Chaushu
Navot Givol
Shlomo Taicher
Source :: Journal of Clinical Periodontology. 24:180-182
Publication Year :: 1997
Publisher :: Wiley, 1997.
Abstract: Vigabatrin is a relatively new medication used in the treatment of epilepsia. The present report concerns the use of vigabatrin by a 19-year-old woman. The patient manifested marked gingival overgrowth compatible clinically and histologically with the overgrowth induced by phenytoin, cyclosporine and calcium channel blockers. This is the 1st report of vigabatrin-induced gingival overgrowth. Clinicians should be aware of similar lesions in patients using new anticonvulsants.