Additional file 7: of HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1

Figure S4. (a) Boxplots showing the expression levels of VEGFA mRNA in breast cancer samples. The samples were stratified based on HMGA1 (left) and FOXM1 (right) mRNA expression levels. (b) and (c) Luciferase assays on HEK293T cells transiently co-transfected with the luciferase reporter plasmid pGL4.10-VEGFprom (− 1000–1) with increasing quantities of either the expression plasmid pEGFP-FOXM1 (b) or pEGFP-HMGA1 (c). pRL-CMV Renilla luciferase expression vector was included to normalize for transfection efficiencies. Values are reported as relative luciferase activity comparing to cells transfected with the expression control vector pEGFP. The data are represented as the mean ± SD (n = 3). **p