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Dry and Wet Prolines for Asymmetric Organic Solvent-Free Aldehyde—Aldehyde and Aldehyde—Ketone Aldol Reactions

Authors :
Yujiro Hayashi
Mitsuru Shoji
Seiji Aratake
Tsubasa Okano
Tatsunobu Sumiya
Takahiko Itoh
Source :
ChemInform. 38
Publication Year :
2007
Publisher :
Wiley, 2007.

Abstract

Dry and wet prolines were found to catalyze the direct aldol reactions of aldehyde–aldehyde and aldehyde–ketone, respectively, to afford aldols with excellent diastereo- and enantioselectivities, and an organic solvent-free reaction was realized in some cases.

Details

ISSN :
15222667 and 09317597
Volume :
38
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi.dedup.....add21dc0fb3b7393d775cdb2999106b4
Full Text :
https://doi.org/10.1002/chin.200728028