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An atypical occurrence of Aspergillosis in leukemic patient: Brief description of a clinical case
- Source :
- Journal de mycologie medicale. 28(4)
- Publication Year :
- 2018
-
Abstract
- Herein we describe a 43 year-old Caucasian female patient with acute myeloid leukemia that developed an unconventional form of invasive Aspergillosis. For therapeutic reasons, a Groshong-type central venous catheter was positioned. Monitoring the patient's clinical conditions, positive values for C-reactive protein and galactomannan were correlated with a probably Aspergillosis. Surprisingly no pulmonary evidences were observed. Due to worsening conditions, she was re-hospitalized and a blood culture was performed, whom positivity resulted as the first clinical evidence of Aspergillus fumigatus. Further evidence about species identification was obtained by sequencing the fungal ITS region. We support the clinical value of blood culture as a decisive factor to improve the diagnosis of catheter-related Aspergillosis.
- Subjects :
- 0301 basic medicine
Adult
Antifungal Agents
Neutropenia
medicine.medical_treatment
030106 microbiology
Aspergillosis
Aspergillus fumigatus
Mannans
03 medical and health sciences
Galactomannan
chemistry.chemical_compound
DNA, Ribosomal Spacer
Medicine
Humans
Blood culture
DNA, Fungal
medicine.diagnostic_test
biology
business.industry
Myeloid leukemia
Galactose
Sequence Analysis, DNA
medicine.disease
biology.organism_classification
Culture Media
Leukemia
Leukemia, Myeloid, Acute
Infectious Diseases
C-Reactive Protein
Treatment Outcome
chemistry
Blood Culture
Catheter-Related Infections
Immunology
Female
Clinical case
business
Central venous catheter
Subjects
Details
- ISSN :
- 17730449
- Volume :
- 28
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal de mycologie medicale
- Accession number :
- edsair.doi.dedup.....ae43e8aa919236ad09a5284983658035