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Isolated ACTH deficiency accompanied by 'primary hypothyroidism' and hyperprolactinaemia
- Source :
- Acta Endocrinologica. 104:397-401
- Publication Year :
- 1983
- Publisher :
- Oxford University Press (OUP), 1983.
-
Abstract
- A 55 year old man with isolated ACTH deficiency is reported. The lesion would appear to be located in the pituitary gland since plasma ACTH and cortisol did not respond to lysine vasopressin and corticotrophin releasing factor (CRF). A fall in T4, a rise in basal values of TSH, prolactin (Prl), LH and FSH, excessive responses of TSH and Prl to TRH, and hyperreactive responses of LH and FSH to LRH were observed. These hormonal changes were examined before and after administration of cortisol. The abnormality in these hormones might be caused by deficiency of long-term glucocorticoid.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
Pituitary gland
endocrine system diseases
Corticotropin-Releasing Hormone
Endocrinology, Diabetes and Metabolism
Lypressin
Thyrotropin
Gonadotropin-Releasing Hormone
Lesion
Basal (phylogenetics)
Endocrinology
Adrenocorticotropic Hormone
Hypothyroidism
Internal medicine
medicine
Humans
Insulin
Thyrotropin-Releasing Hormone
business.industry
Hyperprolactinaemia
Primary hypothyroidism
General Medicine
Metyrapone
Middle Aged
medicine.disease
Prolactin
Thyroxine
medicine.anatomical_structure
medicine.symptom
business
hormones, hormone substitutes, and hormone antagonists
Glucocorticoid
Hormone
medicine.drug
Subjects
Details
- ISSN :
- 1479683X and 08044643
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- Acta Endocrinologica
- Accession number :
- edsair.doi.dedup.....ae54c44ad9241ae16117fb6ba45e024c