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Sirolimus- versus Paclitaxel-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Stenosis
- Source :
- Cardiology. 104:181-185
- Publication Year :
- 2005
- Publisher :
- S. Karger AG, 2005.
-
Abstract
- We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.
- Subjects :
- Adult
Male
Coronary angiography
medicine.medical_specialty
Paclitaxel
Left Main Coronary Artery Stenosis
Coronary Angiography
Coronary Restenosis
Blood Vessel Prosthesis Implantation
Ventricular Dysfunction, Left
chemistry.chemical_compound
Coated Materials, Biocompatible
Internal medicine
medicine
Humans
Stent implantation
Pharmacology (medical)
cardiovascular diseases
Aged
Aged, 80 and over
Sirolimus
business.industry
Coronary Stenosis
Follow up studies
Middle Aged
equipment and supplies
Antineoplastic Agents, Phytogenic
Treatment Outcome
surgical procedures, operative
Multicenter study
chemistry
Cardiology
Female
Stents
Cardiology and Cardiovascular Medicine
business
Immunosuppressive Agents
Follow-Up Studies
medicine.drug
Subjects
Details
- ISSN :
- 14219751 and 00086312
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- Cardiology
- Accession number :
- edsair.doi.dedup.....ae799f6a7686ded2b508aec500f14367