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The effects of fruit consumption in patients with hyperuricaemia or gout
- Source :
- Rheumatology. 58:1133-1141
- Publication Year :
- 2019
- Publisher :
- Oxford University Press (OUP), 2019.
-
Abstract
- The consumption of fructose has gained increased attention as a potential cause of hyperuricaemia since fructose metabolism produces urate as a byproduct. In addition to sucrose and high fructose corn syrup, fresh fruits also contain fructose, suggesting that patients with hyperuricaemia or gout might also avoid fresh fruit. However, the effect of fruits is complex. Some studies reported that fruit intake was associated with gout flares while other studies showed that fruits rather lowered the risk for gout. Thus, fruits should not be simply viewed as a source of fructose. The complexity of fruits is accounted for by several nutrients existing in fruits. Vitamin C, epicatechin, flavonols, potassium and fibre are all nutrients in fruits, and these factors could modify fructose and urate effects. In this review, we discuss clinical studies evaluating the effect of fruit and fruit juice intake on hyperuricaemia and gout, and propose potential mechanisms for how fruit may influence urate levels.
- Subjects :
- Dietary Fiber
musculoskeletal diseases
congenital, hereditary, and neonatal diseases and abnormalities
Sucrose
Gout
Ascorbic Acid
Fructose
Hyperuricemia
Prunus avium
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Rheumatology
medicine
Humans
Pharmacology (medical)
030212 general & internal medicine
Food science
030203 arthritis & rheumatology
Vitamin C
business.industry
High-fructose corn syrup
nutritional and metabolic diseases
food and beverages
medicine.disease
Ascorbic acid
Uric Acid
Fruit and Vegetable Juices
chemistry
Fruit
Uric acid
business
Subjects
Details
- ISSN :
- 14620332 and 14620324
- Volume :
- 58
- Database :
- OpenAIRE
- Journal :
- Rheumatology
- Accession number :
- edsair.doi.dedup.....ae7e9b6f9543f7bd03ead86c9a60e808