Back to Search
Start Over
Modeling effects of diquat under realistic exposure patterns in genetically differentiated populations of the gastropod Lymnaea stagnalis
- Source :
- Philosophical Transactions of the Royal Society B: Biological Sciences, Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2010, 365 (1557), pp.3485-3494. ⟨10.1098/rstb.2010.0047⟩
- Publication Year :
- 2010
- Publisher :
- HAL CCSD, 2010.
-
Abstract
- Pesticide use leads to complex exposure and response patterns in non-target aquatic species, so that the analysis of data from standard toxicity tests may result in unrealistic risk forecasts. Developing models that are able to capture such complexity from toxicity test data is thus a crucial issue for pesticide risk assessment. In this study, freshwater snails from two genetically differentiated populations of Lymnaea stagnalis were exposed to repeated acute applications of environmentally realistic concentrations of the herbicide diquat, from the embryo to the adult stage. Hatching rate, embryonic development duration, juvenile mortality, feeding rate and age at first spawning were investigated during both exposure and recovery periods. Effects of diquat on mortality were analysed using a threshold hazard model accounting for time-varying herbicide concentrations. All endpoints were significantly impaired at diquat environmental concentrations in both populations. Snail evolutionary history had no significant impact on their sensitivity and responsiveness to diquat, whereas food acted as a modulating factor of toxicant-induced mortality. The time course of effects was adequately described by the model, which thus appears suitable to analyse long-term effects of complex exposure patterns based upon full life cycle experiment data. Obtained model outputs (e.g. no-effect concentrations) could be directly used for chemical risk assessment.
- Subjects :
- 0106 biological sciences
Male
ECOLOGICAL RISK ASSESSMENT
Lymnaea stagnalis
010501 environmental sciences
Biology
01 natural sciences
Diquat
General Biochemistry, Genetics and Molecular Biology
Toxicology
chemistry.chemical_compound
PESTICIDES
Toxicity Tests
FRESHWATER GASTROPODS
Juvenile
Animals
0105 earth and related environmental sciences
Lymnaea
Proportional Hazards Models
Hatching
Herbicides
010604 marine biology & hydrobiology
Aquatic animal
Articles
CONCENTRATIONS VARIABLES---HAZARD MODELS
Pesticide
biology.organism_classification
MODELISATION
chemistry
FULL LIFE CYCLE EXPERIMENT
[SDV.TOX]Life Sciences [q-bio]/Toxicology
Toxicity
TIME-VARYING CONCENTRATION
[SDE]Environmental Sciences
Florida
Female
General Agricultural and Biological Sciences
Water Pollutants, Chemical
Subjects
Details
- Language :
- English
- ISSN :
- 09628436 and 14712970
- Database :
- OpenAIRE
- Journal :
- Philosophical Transactions of the Royal Society B: Biological Sciences, Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2010, 365 (1557), pp.3485-3494. ⟨10.1098/rstb.2010.0047⟩
- Accession number :
- edsair.doi.dedup.....af02b25882e8b6d7e8c5e198f427efe4
- Full Text :
- https://doi.org/10.1098/rstb.2010.0047⟩