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Modeling effects of diquat under realistic exposure patterns in genetically differentiated populations of the gastropod Lymnaea stagnalis

Authors :
Alexandre R.R. Pery
Virginie Ducrot
Laurent Lagadic
Laboratoire d'Ecologie Halieutique - Agrocampus Ouest
Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST
Institut National de l'Environnement Industriel et des Risques (INERIS)
Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Source :
Philosophical Transactions of the Royal Society B: Biological Sciences, Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2010, 365 (1557), pp.3485-3494. ⟨10.1098/rstb.2010.0047⟩
Publication Year :
2010
Publisher :
HAL CCSD, 2010.

Abstract

Pesticide use leads to complex exposure and response patterns in non-target aquatic species, so that the analysis of data from standard toxicity tests may result in unrealistic risk forecasts. Developing models that are able to capture such complexity from toxicity test data is thus a crucial issue for pesticide risk assessment. In this study, freshwater snails from two genetically differentiated populations of Lymnaea stagnalis were exposed to repeated acute applications of environmentally realistic concentrations of the herbicide diquat, from the embryo to the adult stage. Hatching rate, embryonic development duration, juvenile mortality, feeding rate and age at first spawning were investigated during both exposure and recovery periods. Effects of diquat on mortality were analysed using a threshold hazard model accounting for time-varying herbicide concentrations. All endpoints were significantly impaired at diquat environmental concentrations in both populations. Snail evolutionary history had no significant impact on their sensitivity and responsiveness to diquat, whereas food acted as a modulating factor of toxicant-induced mortality. The time course of effects was adequately described by the model, which thus appears suitable to analyse long-term effects of complex exposure patterns based upon full life cycle experiment data. Obtained model outputs (e.g. no-effect concentrations) could be directly used for chemical risk assessment.

Details

Language :
English
ISSN :
09628436 and 14712970
Database :
OpenAIRE
Journal :
Philosophical Transactions of the Royal Society B: Biological Sciences, Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2010, 365 (1557), pp.3485-3494. ⟨10.1098/rstb.2010.0047⟩
Accession number :
edsair.doi.dedup.....af02b25882e8b6d7e8c5e198f427efe4
Full Text :
https://doi.org/10.1098/rstb.2010.0047⟩