Back to Search
Start Over
Differences in Walking Pattern during 6-Min Walk Test between Patients with COPD and Healthy Subjects
- Source :
- PLoS ONE, PLoS ONE, Vol 7, Iss 5, p e37329 (2012), PLOS ONE, 7(5):e37329. Public Library of Science
- Publication Year :
- 2012
- Publisher :
- Public Library of Science, 2012.
-
Abstract
- BackgroundTo date, detailed analyses of walking patterns using accelerometers during the 6-min walk test (6MWT) have not been performed in patients with chronic obstructive pulmonary disease (COPD). Therefore, it remains unclear whether and to what extent COPD patients have an altered walking pattern during the 6MWT compared to healthy elderly subjects.Methodology/principal findings79 COPD patients and 24 healthy elderly subjects performed the 6MWT wearing an accelerometer attached to the trunk. The accelerometer features (walking intensity, cadence, and walking variability) and subject characteristics were assessed and compared between groups. Moreover, associations were sought with 6-min walk distance (6MWD) using multiple ordinary least squares (OLS) regression models. COPD patients walked with a significantly lower walking intensity, lower cadence and increased walking variability compared to healthy subjects. Walking intensity and height were the only two significant determinants of 6MWD in healthy subjects, explaining 85% of the variance in 6MWD. In COPD patients also age, cadence, walking variability measures and their interactions were included were significant determinants of 6MWD (total variance in 6MWD explained: 88%).Conclusions/significanceCOPD patients have an altered walking pattern during 6MWT compared to healthy subjects. These differences in walking pattern partially explain the lower 6MWD in patients with COPD.
- Subjects :
- medicine.medical_specialty
Time Factors
Anatomy and Physiology
Pulmonology
Chronic Obstructive Pulmonary Diseases
Science
Walking
Pulmonary Disease, Chronic Obstructive
Physical medicine and rehabilitation
Engineering
Seismic Signal Processing
Diagnostic Medicine
Integrative Physiology
Medicine
Humans
Sports and Exercise Medicine
Gait
Musculoskeletal System
Geriatrics
COPD
Multidisciplinary
business.industry
Case-control study
medicine.disease
Trunk
Intensity (physics)
Biomechanical Phenomena
Gait analysis
Case-Control Studies
Signal Processing
Physical therapy
Exertion
Physiotherapy and Rehabilitation
business
Cadence
human activities
Research Article
Test Evaluation
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 7
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- PLOS ONE
- Accession number :
- edsair.doi.dedup.....af17bf3ffcb8ecb64b3c5111d13c36d7