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Clinical characteristics and outcomes of patients with coronary artery spasm who initially presented with acute myocardial infarction
- Source :
- Coronary Artery Disease. 29:60-67
- Publication Year :
- 2018
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2018.
-
Abstract
- BACKGROUND The long-term clinical outcomes of coronary artery spasm (CAS) patients presented with acute myocardial infarction (AMI) compared to those who did not present with AMI has rarely been investigated. METHODS From November 2004 to May 2014, a total of 3360 patients who were confirmed as CAS by the acetylcholine (Ach) provocation test and without significant coronary lesion were retrospectively analyzed. AMI was an initial presentation in 34 patients [CAS-myocardial infarction (MI) group], and not in other 3326 patients (CAS group). The clinical outcomes up to 5 years were compared between the two groups. RESULTS Baseline characteristics and cardiovascular risk factors did not differ between the two groups, except the higher smoking rate in CAS-MI group (38.2 vs. 23.5%, P=0.046). During a mean follow-up period of 1211±583 days, the cumulative incidence of recurrent angina [hazard ratio (HR): 2.71; 95% confidence interval (CI): 1.20-6.13; P=0.016], MI (HR: 33.89; 95% CI: 8.76-131.1; P
- Subjects :
- Adult
Male
medicine.medical_specialty
Ticlopidine
Myocardial Infarction
Coronary Vasospasm
Infarction
Angiotensin-Converting Enzyme Inhibitors
030204 cardiovascular system & hematology
Angina Pectoris
Angina
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Recurrence
Internal medicine
medicine
Humans
Cumulative incidence
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Propensity Score
Aged
Proportional Hazards Models
Retrospective Studies
Aspirin
business.industry
Incidence
Hazard ratio
General Medicine
Middle Aged
Prognosis
Clopidogrel
medicine.disease
Confidence interval
Logistic Models
Cardiovascular Diseases
Case-Control Studies
Multivariate Analysis
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Platelet Aggregation Inhibitors
Mace
Follow-Up Studies
medicine.drug
Subjects
Details
- ISSN :
- 09546928
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Coronary Artery Disease
- Accession number :
- edsair.doi.dedup.....af6bd0bc5092020371b1e63dd3c4f369