Back to Search
Start Over
Emerging trends from COVID-19 research registered in the Clinical Trials Registry - India
- Source :
- Indian Journal of Medical Research, Vol 153, Iss 1, Pp 26-63 (2021), The Indian Journal of Medical Research
- Publication Year :
- 2021
- Publisher :
- Medknow, 2021.
-
Abstract
- Since the beginning of the year, the deadly coronavirus pandemic, better known as coronavirus disease 2019 (COVID-19), brought the entire world to an unprecedented halt. In tandem with the global scenario, researchers in India are actively engaged in the conduct of clinical research to counter the pandemic. This review attempts to provide a comprehensive overview of the COVID-19 research in India including design aspects, through the clinical trials registered in the Clinical Trials Registry - India (CTRI) till June 5, 2020. One hundred and twenty two registered trials on COVID-19 were extracted from the CTRI database. These trials were categorized into modern medicine (n=42), traditional medicine (n=67) and miscellaneous (n=13). Of the 42 modern medicine trials, 28 were on repurposed drugs, used singly (n=24) or in combination (n=4). Of these 28 trials, 23 were to evaluate their therapeutic efficacy in different severities of the disease. There were nine registered trials on cell- and plasma-based therapies, two phytopharmaceutical trials and three vaccine trials. The traditional medicine trials category majorly comprised Ayurveda (n=45), followed by homeopathy (n=14) and others (n=8) from Yoga, Siddha and Unani. Among the traditional medicine category, 31 trials were prophylactic and 36 were therapeutic, mostly conducted on asymptomatic or mild-to-moderate COVID-19 patients. This review would showcase the research being conducted on COVID-19 in the country and highlight the research gaps to steer further studies.
- Subjects :
- 0301 basic medicine
Modern medicine
medicine.medical_specialty
Biomedical Research
Coronavirus disease 2019 (COVID-19)
convalescent plasma therapy
030106 microbiology
India
CTRI-India
Review Article
Disease
Ayurveda, Yoga and Naturopathy, Unani, Siddha, Homeopathy
General Biochemistry, Genetics and Molecular Biology
homeopathy - clinical trials - ctri-india - convalescent plasma therapy - covid-19 - drug trials - registration - vaccine trials
03 medical and health sciences
0302 clinical medicine
siddha
registration
vaccine trials
yoga and naturopathy
Pandemic
Siddha
medicine
Humans
Registries
030212 general & internal medicine
clinical trials
Clinical Trials as Topic
business.industry
drug trials
COVID-19
unani
General Medicine
Homeopathy
Clinical trial
Clinical research
ayurveda
Family medicine
Medicine
business
Subjects
Details
- ISSN :
- 09715916
- Volume :
- 153
- Database :
- OpenAIRE
- Journal :
- Indian Journal of Medical Research
- Accession number :
- edsair.doi.dedup.....af9228d9b6295a6e1a99e588331946f6