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Polysaccharide extracted from Huperzia serrata using response surface methodology and its biological activity
- Source :
- International Journal of Biological Macromolecules. 157:267-275
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- In this study, Huperzia serrata polysaccharide (HSP) fraction was isolated using response surface methodology (RSM) and Box-Behnken design (BBD). The extraction time, temperature and ratio of water to raw material were employed effects. And properties of four polysaccharide (60%-HSP, 70%-HSP, 80%-HSP and 90%-HSP) were evaluated. The results indicated that the optimal extraction conditions were the following: 3.07 h, 49.46 °C and a liquid material ratio of 20.73:1. The four HSP presented irregular aggregation of shape. And all HSP exhibited antioxidant and anticancer activities.
- Subjects :
- Antioxidant
Surface Properties
medicine.medical_treatment
Antineoplastic Agents
Fraction (chemistry)
02 engineering and technology
Chemical Fractionation
Raw material
Polysaccharide
Biochemistry
Antioxidants
03 medical and health sciences
Polysaccharides
Structural Biology
medicine
Response surface methodology
Molecular Biology
030304 developmental biology
chemistry.chemical_classification
0303 health sciences
Chromatography
biology
Chemistry
Monosaccharides
Extraction (chemistry)
Temperature
Water
Huperzia
Biological activity
General Medicine
Huperzia serrata
021001 nanoscience & nanotechnology
biology.organism_classification
Microscopy, Electron, Scanning
0210 nano-technology
Subjects
Details
- ISSN :
- 01418130
- Volume :
- 157
- Database :
- OpenAIRE
- Journal :
- International Journal of Biological Macromolecules
- Accession number :
- edsair.doi.dedup.....affaea3d97e8526b1f435aa7d1e7bbfb