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Aortopulmonary fistula in a Warmblood mare associated with an aortic aneurysm and supravalvular aortic stenosis
- Source :
- JOURNAL OF VETERINARY INTERNAL MEDICINE, Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 2152-2157 (2020)
- Publication Year :
- 2020
-
Abstract
- This case report describes the clinical presentation, the necropsy findings, and genetic results of a 13‐year‐old Warmblood mare presented with colic and a bilaterally loud, holosystolic murmur. Echocardiographic examination revealed the presence of a thoracic aortic aneurysm, an aortic pseudoaneurysm, a periaortic hematoma (circumferential cuffing by perivascular hemorrhage), and aortopulmonary fistulation. A supravalvular aortic stenosis (SVAS) was visible during echocardiography. Necropsy confirmed that the thoracic aortic aneurysm had ruptured and connected to the pseudoaneurysm, which fistulated into the pulmonary artery. Histologically, the aneurysm wall revealed chronic lesions such as fibrosis, mucin depositions, mineralizations, and elastin fragmentation. The mid abdominal aorta showed lesions suggestive of a systemic elastin arteriopathy. Molecular analysis, however, could not attribute this disease to a variant in the elastin gene, the most common causative gene for SVAS. To the authors' knowledge, this case report describes a case of aortopulmonary fistulation in a Warmblood horse associated with the presence of SVAS and an aortic aneurysm.
- Subjects :
- medicine.medical_specialty
040301 veterinary sciences
elastin gene
030204 cardiovascular system & hematology
Thoracic aortic aneurysm
VALVE
0403 veterinary science
03 medical and health sciences
Aortic aneurysm
Pseudoaneurysm
0302 clinical medicine
Aneurysm
medicine.artery
medicine
cardiovascular diseases
Veterinary Sciences
VITAMIN-D
ELASTIN
equine
lcsh:Veterinary medicine
General Veterinary
biology
business.industry
Abdominal aorta
pseudoaneurysm
04 agricultural and veterinary sciences
medicine.disease
aortic disease
GENE
Pulmonary artery
REGULATORY ELEMENT
biology.protein
cardiovascular system
lcsh:SF600-1100
Radiology
business
Supravalvular aortic stenosis
Elastin
Subjects
Details
- Language :
- English
- ISSN :
- 08916640 and 19391676
- Database :
- OpenAIRE
- Journal :
- JOURNAL OF VETERINARY INTERNAL MEDICINE, Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 2152-2157 (2020)
- Accession number :
- edsair.doi.dedup.....b0ff85db00c3f4e27ad41579f1930187