Rogaratinib in patients with advanced urothelial carcinomas prescreened for tumor FGFR mRNA expression and effects of mutations in the FGFR signaling pathway

Authors :: Heike Richly
Nicolas Penel
Markus Joerger
David Tai
Cyrus Sayehli
Peter Ellinghaus
Martin Schuler
Hendrik Nogai
Lucia Nogova
Richard Cathomas
Alejandro Navarro
Martin Schostak
Philippe A. Cassier
A. Janitzky
Carsten Grüllich
Sebastian Bender
Se Hoon Park
Enrique Grande
Martin Wermke
Publication Year :: 2018
Abstract: 4513Background: Activation of FGFR signaling is involved in a variety of malignancies including advanced urothelial cancer (UC). Rogaratinib is an oral pan-FGFR kinase inhibitor. We report here the...

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