Two cases of long term dopamine D2 receptor blockade after depot neuroleptics

Authors :: Thomas Brücke
P. Fischer
Lüder Deecke
Ivo Podreka
S. Wenger
C. Harasko-van der Meer
Source :: Journal of neural transmission. General section. 94(3)
Publication Year :: 1993
Abstract: Two patients with extrapyramidal side effects after the use of fluphenazine decanoate were evaluated by means of IBZM-SPECT. Dopamine D2 receptor occupancy 1.5 months after withdrawal still amounted to 83% and 50%. More attention should be focused on long term effects of neuroleptics.

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