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In-Host Adaptation of Salmonella enterica Serotype Dublin during Prosthetic Hip Joint Infection

Authors :
Martin Rottman
Thomas W. Bauer
Nizar Fawal
Aurelia Gruber
Caroline Dupont
Guillaume Sapriel
Henri-Jean Garchon
Simon Le Hello
Faten El Sayed
Beate Heym
Jean-Louis Gaillard
Hôpital Ambroise Paré [AP-HP]
Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)
Atelier de BioInformatique (ABI)
Sorbonne Université (SU)
Centre National de Référence - National Reference Center Escherichia coli, Shigella et Salmonella (CNR-ESS)
Institut Pasteur [Paris]
Hôpital Raymond Poincaré [AP-HP]
This work was supported by the French National Reference Center for Escherichia coli, Shigella, and Salmonella, co-funded by Santé Publique France and belonging to the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence funded by the French Government Investissement d’Avenir program (grant no. ANR-10-LABX-62-IBEID).
ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)
Institut Pasteur [Paris] (IP)
Source :
Emerging Infectious Diseases, Vol 24, Iss 12, Pp 2360-2363 (2018), Emerging Infectious Diseases, Emerging Infectious Diseases, Centers for Disease Control and Prevention, 2018, 24 (12), pp.2360-2363. ⟨10.3201/eid2412.180214⟩, Emerging Infectious Diseases, 2018, 24 (12), pp.2360-2363. ⟨10.3201/eid2412.180214⟩
Publication Year :
2018
Publisher :
Centers for Disease Control and Prevention, 2018.

Abstract

International audience; Genome degradation has been central to the adaptation of Salmonella enterica serotypes to their hosts throughout evolution. We witnessed the patho-adaptation of a strain of Salmonella Dublin (a cattle-adapted serotype) to a human host during the course of a recurrent prosthetic hip joint infection evolving over several years.

Details

Language :
English
ISSN :
10806059 and 10806040
Volume :
24
Issue :
12
Database :
OpenAIRE
Journal :
Emerging Infectious Diseases
Accession number :
edsair.doi.dedup.....b25d7a293c7fd7431bae5bf2f8c3fd97
Full Text :
https://doi.org/10.3201/eid2412.180214⟩