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Hoxb5, a Trojan horse to generate T cells

Authors :
Thomas Graf
Gregoire Stik
Source :
Nature Immunology
Publication Year :
2018

Abstract

The transcription factor Hoxb5 is expressed specifically in hematopoietic stem cells, yet its ectopic expression in mouse B cell progenitors induces their conversion into functional T cells in vivo.

Details

ISSN :
15292908
Database :
OpenAIRE
Journal :
Nature Immunology
Accession number :
edsair.doi.dedup.....b335b0fb1a807eeab2a87152c5d5313a
Full Text :
https://doi.org/10.1038/s41590-018-0053-y