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Lung cancer risk among bakers, pastry cooks and confectionary makers: the SYNERGY study

Authors :
Maria Teresa Landi
Per Gustavsson
John R. McLaughlin
Hans Erich Wichmann
Tabea Treppmann
David Zaridze
Florence Guida
Kurt Straif
Roel Vermeulen
Nils Plato
Eleonora Fabianova
Lap Ah Tse
Marie-Élise Parent
Vladimir Janout
Peter Rudnai
Vladimir Bencko
Neil E. Caporaso
Ann Olsson
Neil Pearce
Adonina Tardón
Paolo Boffetta
Isabelle Stücker
Lorenzo Richiardi
Dario Consonni
Rodica Stanescu Dumitru
Andrea 't Mannetje
Thomas Behrens
Neonila Szeszenia-Dabrowska
Karl-Heinz Jöckel
Franco Merletti
Ignatius Tak-sun Yu
Bas Bueno-de-Mesquita
Dario Mirabelli
Simone Benhamou
Jolanta Lissowska
Hermann Pohlabeln
Hans Kromhout
Susan Peters
Lenka Foretova
John K. Field
Joachim Schüz
Irene Brüske
Lorenzo Simonato
Thomas Brüning
Wolfgang Ahrens
Beate Pesch
Benjamin Kendzia
Jack Siemiatycki
Paul A. Demers
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)
Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC)
Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)
The Institute of Environmental Medicine [Stockholm] (IMM)
Karolinska Institutet [Stockholm]
Institute for Medical Informatics, Biometry and Epidemiology
University Hospital of Essen
Leibniz Institute for Prevention Research and Epidemiology - BIPS
Leibniz Association
Institute for Statistics
University of Bremen
Institute of Epidemiology I
German Research Center for Environmental Health-Helmholtz-Zentrum München (HZM)
Cancer Epidemiology Unit
Université de Turin
Department of Environmental Medicine and Public Health
Universita degli Studi di Padova
Institute of Carcinogenesis
Russian Academy of Medical Sciences
The Nofer Institute of Occupational Medicine
National Institute of Environmental Health
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
Regional Authority of Public Health [Slovaquia] (RAPH)
Ministry of Health of the Slovak Republic [Slovaquia]
Molecular Epidemiology of Cancer Unit
CIBER de Epidemiología y Salud Pública (CIBERESP)
Roy Castle Lung Cancer Research Programme
University of Liverpool
National Institute of Public Health [Romania] (INSP)
Institute of Hygiene and Epidemiology
Charles University [Prague] (CU)-1st Faculty of Medicine
Department of Cancer Epidemiology and Genetics
Masaryk Memorial Cancer Institute (RECAMO)
Faculty of Medicine
Palacky University Olomouc
Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CR CHUM)
Centre Hospitalier de l'Université de Montréal (CHUM)
Université de Montréal (UdeM)-Université de Montréal (UdeM)
Institut Armand Frappier (INRS-IAF)
Réseau International des Instituts Pasteur (RIIP)-Institut National de la Recherche Scientifique [Québec] (INRS)
Cancer Care Ontario
Occupational Cancer Research Centre
National Cancer Institute [Bethesda] (NCI-NIH)
National Institutes of Health [Bethesda] (NIH)
Division of Environmental Epidemiology
Utrecht University [Utrecht]-Institute of Risk Assessment Sciences
Western Australian Institute for Medical Research
The University of Western Australia (UWA)
Variabilité Génétique et Maladies Humaines
Institut Universitaire d'Hématologie (IUH)
Université Paris Diderot - Paris 7 (UPD7)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Centre de recherche en épidémiologie et santé des populations (CESP)
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)
University Paris-Sud
Unit of Epidemiology
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
National Institute for Public Health and the Environment [Bilthoven] (RIVM)
Centre for Public Health Research
Faculty of Epidemiology and Population Health [London]
London School of Hygiene and Tropical Medicine (LSHTM)
Division of Occupational and Environmental Health
JC School of Public Health and Primary Care
The Chinese University of Hong Kong [Hong Kong]-The Chinese University of Hong Kong [Hong Kong]
The Tisch Cancer Institute
Icahn School of Medicine at Mount Sinai [New York] (MSSM)
International Prevention Research Institute (IPRI)
This study was supported by the German Social Accident Insurance, grant FP 271. Grant sponsors of the individual studies were the Canadian Institutes of Health Research and Guzzo-SRC Chair in Environment and Cancer, the Fondation de France, the German Federal Ministry of Education, Science, Research, and Technology and the Ministry of Labour and Social Affairs, the EC's INCO-COPERNICUS Program, the Polish State Committee for Science Research, the Roy Castle Foundation, the NIH/NCI/DCEG Intramural Research Program, Lombardy Region, INAIL and the European Union Nuclear Fission Safety Program, the Italian Association for Cancer Research, Region Piedmont, the Compagnia di San Paolo, the Europe Against Cancer Program, the Swedish Council for Work Life Research and the Swedish EPA, the University of Oviedo, the European Regional Development Fund and the State Budget of the Czech Republic (RECAMO, CZ.1.05/2.1.00/03.0101), CIBERESP and FISS-PI060604.
Behrens, T.
Kendzia, B.
Treppmann, T.
Olsson, A.
Jöckel, K.-H.
Gustavsson, P.
Pohlabeln, H.
Ahrens, W.
Brüske, I.
Wichmann, H.-E.
Merletti, F.
Mirabelli, D.
Richiardi, L.
Simonato, L.
Zaridze, D.
Szeszenia-Dabrowska, N.
Rudnai, P.
Lissowska, J.
Fabianova, E.
Tardón, A.
Field, J.
Dumitru, R.S.
Bencko, V.
Foretova, L.
Janout, V.
Siemiatycki, J.
Parent, M.-E.
McLaughlin, J.
Demers, P.
Landi, M.T.
Caporaso, N.
Kromhout, H.
Vermeulen, R.
Peters, S.
Benhamou, S.
Stücker, I.
Guida, F.
Consonni, D.
Bueno-de-Mesquita, B.
Mannetje, A.'.
Pearce, N.
Tse, L.A.
Yu, I.T.-S.
Plato, N.
Boffetta, P.
Straif, K.
Schüz, J.
Pesch, B.
Brüning, T.
Source :
Occupational and Environmental Medicine, Occupational and Environmental Medicine, BMJ Publishing Group, 2013, 70 (11), pp.810-4. ⟨10.1136/oemed-2013-101469⟩, Occup Environ Med
Publication Year :
2013
Publisher :
HAL CCSD, 2013.

Abstract

Introduction Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case–control database from 16 countries. Methods Occupation in a baking-related job was identified from the subjects’ job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion The findings from this study do not suggest increased lung cancer risks in baking-related professions.

Details

Language :
English
ISSN :
13510711
Database :
OpenAIRE
Journal :
Occupational and Environmental Medicine, Occupational and Environmental Medicine, BMJ Publishing Group, 2013, 70 (11), pp.810-4. ⟨10.1136/oemed-2013-101469⟩, Occup Environ Med
Accession number :
edsair.doi.dedup.....b349d48b372b6416a1058b91445b6282
Full Text :
https://doi.org/10.1136/oemed-2013-101469⟩