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Post-stroke Hyperglycemia in Non-diabetic Ischemic Stroke is Related With Worse Functional Outcome: A Cohort Study
- Source :
- Annals of Rehabilitation Medicine, Vol 45, Iss 5, Pp 359-367 (2021), Annals of Rehabilitation Medicine
- Publication Year :
- 2021
- Publisher :
- Korean Academy of Rehabilitation Medicine, 2021.
-
Abstract
- Objective To investigate long-term and serial functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia.Methods The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) is a large, multi-center, prospective cohort study of stroke patients admitted to participating hospitals in nine areas of Korea. From KOSCO, ischemic stroke patients without diabetes were recruited and divided into two groups: patients without diabetes without (n=779) and with post-stroke hyperglycemia (n=223). Post-stroke hyperglycemia was defined as a glucose level >8 mmol/L. Functional assessments were performed 7 days and 3, 6, and 12 months after stroke onset.Results There were no significant differences in baseline characteristics between the groups, except in the age of onset and smoking. Analysis of the linear correlation between the initial National Institutes of Health Stroke Scale (NIHSS) score and glucose level showed no significant difference. Among our functional assessments, NIHSS, Fugl-Meyer Assessment (affected side), Functional Ambulatory Category, modified Rankin Scale, and Korean Mini-Mental State Examination (K-MMSE) showed statistically significant improvements in each group. All functional improvements except K-MMSE were significantly higher in patients without post-stroke hyperglycemia at 7 days and 3, 6, and 12 months.Conclusion The glucose level of ischemic stroke patients without diabetes had no significant correlation with the initial NIHSS score. The long-term effects of stress hyperglycemia showed worse functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia.
- Subjects :
- medicine.medical_specialty
business.industry
Rehabilitation
recovery of function
Stress hyperglycemia
medicine.disease
cohort studies
Modified Rankin Scale
Internal medicine
Diabetes mellitus
Ambulatory
Cohort
medicine
ischemic stroke
Medicine
Original Article
cardiovascular diseases
hyperglycemia
Prospective cohort study
business
Stroke
Cohort study
Subjects
Details
- Language :
- English
- ISSN :
- 22340653 and 22340645
- Volume :
- 45
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Annals of Rehabilitation Medicine
- Accession number :
- edsair.doi.dedup.....b36ee10d8aa013a3e01b1d5a44dfb8fb