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Long-Term Results of In Situ Split-Liver Transplantation
- Source :
- Transplantation Proceedings. 37:2592-2594
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Background Split-liver transplantation (SLT) offers immediate expansion of the cadaver donor pool. The principal beneficiaries have been adult and pediatric recipients with excellent outcomes. This study analyzed a single-center experience of adult to adult in situ SLT in adult recipients. Patients and methods Fourteen consecutive adult-to-adult in situ SLT have been performed at our institution since 1998. The extended right lobe comprising segment 1 was transplanted in to adult patients, the left lateral segment, for pediatric transplants. Results Donors of SLT were significantly younger ( P = .03) than those of whole liver transplants. Survival rates of patients receiving a split liver were 83%, 73%, and 73% at 1, 3, and 5 years after the transplant respectively and grafts of 73%, 73%, and 73% for SLT and 76%, 70%, and 66% for whole liver transplants ( P = .44). The rate of biliary complication after SLT was 21%, which was comparable to that after whole organ transplantation (17%). The incidence of hepatic artery thrombosis and primary nonfunction was not significantly different between split liver and whole organ transplantation performed during the same time period (7% versus 4.6% P = .67 and 7% versus 2.6% P = .32, respectively). Conclusion This limited single-center experience confirmed that both early and long-term results of SLT are comparable to those of traditional whole liver organ transplantation.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
genetic structures
Organ transplantation
Hepatectomy
Humans
Medicine
Child
Retrospective Studies
Immunosuppression Therapy
Transplantation
Adult patients
business.industry
Liver Diseases
Incidence (epidemiology)
Whole liver
Long term results
Middle Aged
Cadaver donor
Liver Transplantation
Surgery
Treatment Outcome
Split liver transplantation
Tissue and Organ Harvesting
Female
business
Subjects
Details
- ISSN :
- 00411345
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Transplantation Proceedings
- Accession number :
- edsair.doi.dedup.....b3e34c08452cb234a7e6275992ca31fd