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Giant hidradenocarcinoma: a report of malignant transformation from nodular hidradenoma
- Source :
- Pathology international. 48(10)
- Publication Year :
- 1998
-
Abstract
- A giant hidradenocarcinoma presented by a 75-year-old female is reported. The patient had a malignant transformation within a nodular hidradenoma involving the right postauricular area, which was treated by mass removal and a right radical neck dissection with a free-flap covering. Malignant hidradenocarcinoma is the least common adnexal tumor of uncertain origin. They are usually malignant from their inception, but some develop from a benign counterpart. To the authors' knowledge, only three cases have been reported previously. Two histologically distinct components were seen in this tumor: (i) typical nodular hidradenoma, which constituted a small part of the tumor; and (ii) carcinoma with areas of transition. The secretory cells of hidradenocarcinoma showed decapitation secretion on light and electron microscopic observations, which is evidence of apocrine differentiation. Histologically, this case was concluded as a hidradenocarcinoma arising from a long-standing nodular hidradenoma. A literature review is presented and the histological, immunohistochemical and ultrastructural features are described.
- Subjects :
- Nodular Hidradenoma
Pathology
medicine.medical_specialty
Mass removal
Adenoma
business.industry
Apocrine Differentiation
Adenoma, Sweat Gland
medicine.medical_treatment
Neck dissection
General Medicine
medicine.disease
Hidradenocarcinoma
Pathology and Forensic Medicine
Malignant transformation
Sweat Gland Neoplasms
Cell Transformation, Neoplastic
Face
Carcinoma
Medicine
Humans
Female
business
Aged
Subjects
Details
- ISSN :
- 13205463
- Volume :
- 48
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Pathology international
- Accession number :
- edsair.doi.dedup.....b4965dd79d48bfe7b7f95dc8e009a84d