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Bipolar subtypes and their clinical correlates in a sample of 391 bipolar individuals
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Differences between BD-I and BD-II patients with regard to specific illness characteristics are poorly understood. This study is mainly aimed to compare socio-demographic and clinical characteristics between BD-I and BD-II patients with the goal of clarifying possible predictors of clinical course. The sample of this cohort study is composed of 391 currently euthymic bipolar patients. Participants were all receiving only maintenance treatment; their psychopharmacological regimens and psychopathological conditions were stable at assessment. After univariate analyses, BD-II patients were more likely to be female, had more frequently a recent depressive episode and substance abuse/dependence relative to BD-I subjects. BD-II patients were also less likely to have a positive history of psychiatric conditions in family, psychotic symptoms at first episode, and first depressive illness episode. Moreover, BD-II were older at their illness onset and first treatment than BD-I patients. Furthermore, BD-I were more likely to have higher depressive, manic, anxiety, and symptoms severity than BD-II patients. After logistic regression analyses, being female (OR = 0.289), having psychiatric conditions in family (OR = 0.273), and higher severity of illness at CGI (OR = 0.604) were all significantly associated with BD-II. Additional studies are required to replicate these results, and facilitate the prediction of BD outcomes according to the specified profile.
- Subjects :
- Adult
Male
medicine.medical_specialty
Bipolar disorder type II
Bipolar Disorder
Substance-Related Disorders
Anxiety
Logistic regression
Cohort Studies
03 medical and health sciences
Bipolar subtypes
0302 clinical medicine
Sex Factors
Clinical course
Severity of illness
medicine
Humans
Psychiatry
Biological Psychiatry
Demography
First episode
Univariate analysis
Depressive Disorder
Clinical characteristics
business.industry
Middle Aged
medicine.disease
Bipolar disorder type I
Cyclothymic Disorder
Bipolar disorder type I, Bipolar disorder type II, Bipolar subtypes, Clinical characteristics, Clinical course
030227 psychiatry
Substance abuse
Psychiatry and Mental health
Psychotic Disorders
Socioeconomic Factors
bipolar disorder type i
bipolar disorder type ii
bipolar subtypes
clinical characteristics
clinical course
adult
anxiety
bipolar disorder
cohort studies
cyclothymic disorder
demography
depressive disorder
female
humans
male
middle aged
psychotic disorders
substance-related disorders
sex factors
socioeconomic factors
Female
medicine.symptom
business
030217 neurology & neurosurgery
Psychopathology
Cohort study
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....b52172aeb659af84c10f9cfb239de52a