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Characterization of Mycobacterium bovis Phagosome
- Source :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP
- Publication Year :
- 2008
- Publisher :
- Oxford University Press (OUP), 2008.
-
Abstract
- Mycobacterium tuberculosis complex are among the most successful pathogens. Their success resides in the ability to interfere with intracellular traffic avoiding natural pathways of the phagosome maturation. Recently, mycobacteria escape from the phagosome to the cytosol was investigated as an alternative survival strategy. In this context we decided to determine the exact intracellular location of Mycobacterium bovis in different host macrophages and characterize the pathogen intracellular niche for survival. The main goal here was to characterize live vs dead M. bovis spp phagosome in different host macrophages. Macrophages infection, fluorescence and EM procedures were carried out as described previously.
- Subjects :
- 010302 applied physics
Microscopy
Mycobacterium bovis
biology
Chemistry
Materials Science, Multidisciplinary
02 engineering and technology
021001 nanoscience & nanotechnology
biology.organism_classification
01 natural sciences
3. Good health
Microbiology
0103 physical sciences
0210 nano-technology
Instrumentation
Phagosome
Subjects
Details
- ISSN :
- 14358115 and 14319276
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Microscopy and Microanalysis
- Accession number :
- edsair.doi.dedup.....b56b35d299322971ca608871b6ae2247