Copper-catalyzed O-alkenylation of phosphonates

Authors :: Martín Fañanás-Mastral
Nuria Vázquez-Galiñanes
Patricia Gómez-Roibás
Mariña Andón-Rodríguez
Universidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares
Universidade de Santiago de Compostela. Departamento de Química Orgánica
Source :: Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 611-615 (2020), Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela, instname
Publication Year :: 2020
Publisher :: Beilstein Institut, 2020.
Abstract: Copper catalysis allows the direct oxygen alkenylation of dialkyl phosphonates with alkenyl(aryl)iodonium salts with selective transfer of the alkenyl group. This novel methodology proceeds with a wide range of phosphonates under mild conditions and gives straightforward access to valuable enol phosphonates in very good yields. Financial support from the AEI (CTQ2017-88451-R), Xunta de Galicia (ED431F 2016/006; ED431C 2018/04; Centro singular de investigación de Galicia accreditation 2016-2019, ED431G/09) and the European Union (ERDF) is gratefully acknowledged. N. V.-G. thanks AEI for a predoctoral FPI fellowship SI

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