New risk and protective factors for severe hypoglycaemia in people with type 1 diabetes

To evaluate risk factors for severe hypoglycaemia (SH) in patients with type 1 diabetes (T1DM).Retrospective observational and comparative study. All SH occurring between 2007 and 2014 in a German population (Lippe-Detmold) were captured. Characteristics of patients with T1DM and SH were compared with a control group being equivalent concerning age, diabetes duration, HbA1c, comorbidity, and β-blocker treatment. SH was defined as a symptomatic event requiring treatment with intravenous glucose or glucagon administration and being confirmed by a blood glucose measurement of