Back to Search Start Over

Acute acral eruptions in children during the COVID-19 pandemic: Characteristics of 103 children and their family clusters

Authors :
Catherine McCuaig
A. Phan
A. Labarelle
M. Bissuel
Annabel Maruani
Sébastien Barbarot
A. Bellissen
Maryam Piram
Stéphanie Mallet
Bruno Giraudeau
Denis Jullien
L. Monitor
J. Rapp
S. Leducq
Ludovic Martin
Pierre Vabres
Christine Chiaverini
C Lesort
Audrey Lasek
Thomas Hubiche
Hélène Aubert
I. Nicol
L. Fertitta
Centre Hospitalier Universitaire de Nice (CHU Nice)
Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS)
Hospices Civils de Lyon (HCL)
MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE)
Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques
Université de Nantes (UN)-Université de Nantes (UN)
CHU Necker - Enfants Malades [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Centre hospitalier universitaire de Nantes (CHU Nantes)
Physiopathologie des Adaptations Nutritionnelles (PhAN)
Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE)
Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
CHU Trousseau [Tours]
Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)
Groupe Hospitalier de l'Institut Catholique de Lille (GHICL)
CHU Marseille
CHU Sainte Justine [Montréal]
Centre Hospitalier Universitaire d'Angers (CHU Angers)
PRES Université Nantes Angers Le Mans (UNAM)
Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
Hôpital Edouard Herriot [CHU - HCL]
CHU Dijon
Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon)
Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques
Source :
Annales de Dermatologie et de Vénéréologie, Annales de Dermatologie et de Vénéréologie, Elsevier Masson, 2021, 148 (2), pp.94-100. ⟨10.1016/j.annder.2020.11.005⟩, Annales De Dermatologie et De Venereologie
Publication Year :
2021
Publisher :
HAL CCSD, 2021.

Abstract

Background A marked increase in frequency of acute acral eruptions (AAE) was observed in children during the COVID-19 pandemic in the spring period. Objectives In this observational multicenter study, based on children with AAE, we aimed to assess the proportion of household members possibly infected by SARS-CoV-2. Methods We collected data from all children observed with AAE, prospectively from April 7, 2020 to June 22, 2020, and retrospectively since February 28, 2020. The primary outcome was the household infection rate, defined as the proportion of family clusters having at least one member with COVID-19 infection other than the child with AAE (“index child”). The definition of a case was based on characteristic clinical signs and a positive PCR or serology. Results The study included 103 children in 10 French departments and in Quebec. The median age was 13 years and the interquartile range [8–15], with a female-to-male ratio of 1/1.15. In children with AAE, all PCR tests were negative (n = 18), and serology was positive in 2/14 (14.3%) cases. We found no significant anomalies in the lab results. A total of 66 of the 103 families (64.1%) of included children had at least one other infected member apart from the index child. The total number of household members was 292, of whom 119 (40.8%) were considered possibly infected by SARS-CoV-2. No index children or households exhibited severe COVID-19. Discussion Among the 103 households included, 64.1% had at least one infected member. Neither children with AAE nor their households showed severe COVID-19.

Details

Language :
English
ISSN :
01519638
Database :
OpenAIRE
Journal :
Annales de Dermatologie et de Vénéréologie, Annales de Dermatologie et de Vénéréologie, Elsevier Masson, 2021, 148 (2), pp.94-100. ⟨10.1016/j.annder.2020.11.005⟩, Annales De Dermatologie et De Venereologie
Accession number :
edsair.doi.dedup.....b6a67b086f67f691a501fc1a0da2bed0
Full Text :
https://doi.org/10.1016/j.annder.2020.11.005⟩