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Acute acral eruptions in children during the COVID-19 pandemic: Characteristics of 103 children and their family clusters
- Source :
- Annales de Dermatologie et de Vénéréologie, Annales de Dermatologie et de Vénéréologie, Elsevier Masson, 2021, 148 (2), pp.94-100. ⟨10.1016/j.annder.2020.11.005⟩, Annales De Dermatologie et De Venereologie
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- Background A marked increase in frequency of acute acral eruptions (AAE) was observed in children during the COVID-19 pandemic in the spring period. Objectives In this observational multicenter study, based on children with AAE, we aimed to assess the proportion of household members possibly infected by SARS-CoV-2. Methods We collected data from all children observed with AAE, prospectively from April 7, 2020 to June 22, 2020, and retrospectively since February 28, 2020. The primary outcome was the household infection rate, defined as the proportion of family clusters having at least one member with COVID-19 infection other than the child with AAE (“index child”). The definition of a case was based on characteristic clinical signs and a positive PCR or serology. Results The study included 103 children in 10 French departments and in Quebec. The median age was 13 years and the interquartile range [8–15], with a female-to-male ratio of 1/1.15. In children with AAE, all PCR tests were negative (n = 18), and serology was positive in 2/14 (14.3%) cases. We found no significant anomalies in the lab results. A total of 66 of the 103 families (64.1%) of included children had at least one other infected member apart from the index child. The total number of household members was 292, of whom 119 (40.8%) were considered possibly infected by SARS-CoV-2. No index children or households exhibited severe COVID-19. Discussion Among the 103 households included, 64.1% had at least one infected member. Neither children with AAE nor their households showed severe COVID-19.
- Subjects :
- Male
Vasculitis
Acral erythema
Coronavirus disease 2019 (COVID-19)
Adolescent
Hidradenitis
Mucinoses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
[SDV]Life Sciences [q-bio]
Dermatology
Serology
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Interquartile range
Pandemic
medicine
Humans
Family
Lymphocytes
Chilblains
Child
Children
Pandemics
Retrospective Studies
Skin
business.industry
COVID-19
medicine.disease
3. Good health
Multicenter study
Erythema
Antibodies, Antinuclear
Immunoglobulin G
Observational study
Original Article
Female
business
Demography
Familial transmission
Subjects
Details
- Language :
- English
- ISSN :
- 01519638
- Database :
- OpenAIRE
- Journal :
- Annales de Dermatologie et de Vénéréologie, Annales de Dermatologie et de Vénéréologie, Elsevier Masson, 2021, 148 (2), pp.94-100. ⟨10.1016/j.annder.2020.11.005⟩, Annales De Dermatologie et De Venereologie
- Accession number :
- edsair.doi.dedup.....b6a67b086f67f691a501fc1a0da2bed0
- Full Text :
- https://doi.org/10.1016/j.annder.2020.11.005⟩