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Immunomodulatory Effects of Nanoparticles on Skin Allergy
- Source :
- Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017), Scientific Reports
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- In recent years there has been considerable effort to understand the interaction of nanomaterials with the skin. In this study we use an in vivo mouse model of allergic contact dermatitis to investigate how nanoparticles (NPs) may alter allergic responses in skin. We investigate a variety of NPs that vary in size, charge and composition. Results show that small (
- Subjects :
- Male
0301 basic medicine
Skin Absorption
Science
Nanoparticle
02 engineering and technology
medicine.disease_cause
Article
Immunomodulation
03 medical and health sciences
Immune system
In vivo
medicine
Animals
Mast Cells
Skin allergy
Allergic contact dermatitis
Immunosuppressive effect
Mice, Hairless
Multidisciplinary
Chemistry
technology, industry, and agriculture
Degranulation
021001 nanoscience & nanotechnology
medicine.disease
Mice, Inbred C57BL
Disease Models, Animal
030104 developmental biology
Dermatitis, Allergic Contact
Allergic response
Immunology
Biophysics
Nanoparticles
Medicine
Dinitrofluorobenzene
Female
0210 nano-technology
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....b70022301e0b2d58bfaafce78cf7a763
- Full Text :
- https://doi.org/10.1038/s41598-017-03729-2