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Improved Detection of the Sickle Mutation by DNA Analysis

Authors :
Stuart H. Orkin
Corinne D. Boehm
Peter F. R. Little
H H Kazazian
Source :
New England Journal of Medicine. 307:32-36
Publication Year :
1982
Publisher :
Massachusetts Medical Society, 1982.

Abstract

DETECTION of sickle hemoglobin in the human fetus was first accomplished nearly 10 years ago.1 , 2 This marked the beginning of a technology for prenatal diagnosis of the hemoglobinopathies. When m...

Details

ISSN :
15334406 and 00284793
Volume :
307
Database :
OpenAIRE
Journal :
New England Journal of Medicine
Accession number :
edsair.doi.dedup.....b7021739eabcbb574e218e58a81b5667
Full Text :
https://doi.org/10.1056/nejm198207013070106