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FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions

Authors :
Harukazu Suzuki
Hideya Kawaji
Piotr J. Balwierz
Piero Carninci
David A. Hume
Michiel Jl de Hoon
Erik van Nimwegen
Timo Lassmann
Alistair R. R. Forrest
Yoshihide Hayashizaki
Andrew Waterhouse
Carsten O. Daub
Jessica Severin
Source :
Genome biology, Severin, J, Waterhouse, A M, Kawaji, H, Lassmann, T, van Nimwegen, E, Balwierz, P J, de Hoon, M J L, Hume, D A, Carninci, P, Hayashizaki, Y, Suzuki, H, Daub, C O & Forrest, A R R 2009, ' FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions ', Genome Biology, vol. 10, no. 4, pp. paper R39 . https://doi.org/10.1186/gb-2009-10-4-r39, Genome Biology
Publication Year :
2009

Abstract

EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets.<br />EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets that requires minimal development for new data types and search patterns. The FANTOM4 EdgeExpress database summarizes gene expression patterns in the context of alternative promoter structures and regulatory transcription factors and microRNAs using intuitive gene-centric and sub-network views. This is an important resource for gene regulation in acute myeloid leukemia, monocyte/macrophage differentiation and human transcriptional networks.

Details

Volume :
10
Issue :
4
Database :
OpenAIRE
Journal :
Genome biology
Accession number :
edsair.doi.dedup.....b72194ed25ee783aa2bd6304d863d0c3
Full Text :
https://doi.org/10.1186/gb-2009-10-4-r39