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Tenofovir versus tenofovir plus entecavir for chronic hepatitis B with lamivudine resistance and entecavir resistance

Authors :
Seung Up Kim
Do Young Kim
S. Lee
Beom Kyung Kim
Jun Yong Park
Kwang Hyub Han
H. J. Ku
Kyu Sik Jung
Sang Hoon Ahn
Oidov Baatarkhuu
Source :
Journal of Viral Hepatitis. 24:141-147
Publication Year :
2016
Publisher :
Wiley, 2016.

Abstract

Summary We compared the viral suppressive efficacy of tenofovir disoproxil fumarate (TDF) mono-rescue therapy (TDF group) and TDF plus entecavir (ETV) combination-rescue therapy (TDF + ETV group) in chronic hepatitis B (CHB) patients with lamivudine resistance and entecavir resistance. One hundred and thirty-three CHB patients with lamivudine and entecavir resistance were investigated. Ninety-six patients were treated with TDF and 37 with TDF + ETV for at least 6 months. We compared the virologic response rate (HBV DNA level

Details

ISSN :
13520504
Volume :
24
Database :
OpenAIRE
Journal :
Journal of Viral Hepatitis
Accession number :
edsair.doi.dedup.....b7549e55786f54b70836e60d5a3db26e
Full Text :
https://doi.org/10.1111/jvh.12623