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Could the infiltration of the thyroarytenoid muscle define the pT2 glottic carcinoma?
- Source :
- Head & Neck. 41:3639-3646
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Background The involvement of the thyroarytenoid (TA) muscle by glottic cancer may be related to an impaired vocal cord mobility, which is classified as cT2 disease. The primary endpoint was to evaluate the prognostic significance of TA muscle involvement in early glottic cancer treated with transoral laser microsurgery (TLM). Methods A review was conducted on a cohort of 209 patients consecutively treated with TLM for early glottic carcinoma. Univariate analysis was used to examine the prognostic meaning of clinical and pathological parameters. Results The statistical analysis showed that TA muscle infiltration correlated significantly with a worse prognosis in terms of recurrence rate and disease-free survival, and this was confirmed even in the subcohort with pT1a glottic cancer. Conclusions Our preliminary findings suggest that it could be considered as a criterion for upstaging a glottic cancer from pT1 to pT2.
- Subjects :
- Male
Glottis
Microsurgery
medicine.medical_specialty
Cord
Urology
Disease
Disease-Free Survival
Cohort Studies
03 medical and health sciences
0302 clinical medicine
otorhinolaryngologic diseases
Clinical endpoint
Humans
Medicine
Neoplasm Invasiveness
Thyroarytenoid muscle
Transoral laser microsurgery
030223 otorhinolaryngology
Laryngeal Neoplasms
Pathological
Aged
Neoplasm Staging
Retrospective Studies
Univariate analysis
business.industry
Biopsy, Needle
Middle Aged
respiratory system
Prognosis
Immunohistochemistry
Survival Analysis
Treatment Outcome
Otorhinolaryngology
030220 oncology & carcinogenesis
Cohort
Carcinoma, Squamous Cell
Female
Laser Therapy
Laryngeal Muscles
business
Vocal Cord Paralysis
Subjects
Details
- ISSN :
- 10970347 and 10433074
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Head & Neck
- Accession number :
- edsair.doi.dedup.....b79b9ec13e504f602f0dc890b3ce6b05