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Incidence of Chlamydia trachomatis infection in women in England: two methods of estimation
- Source :
- Epidemiology and Infection
- Publication Year :
- 2013
- Publisher :
- Cambridge University Press, 2013.
-
Abstract
- SUMMARYInformation on the incidence of Chlamydia trachomatis (CT) is essential for models of the effectiveness and cost-effectiveness of screening programmes. We developed two independent estimates of CT incidence in women in England: one based on an incidence study, with estimates ‘recalibrated’ to the general population using data on setting-specific relative risks, and allowing for clearance and re-infection during follow-up; the second based on UK prevalence data, and information on the duration of CT infection. The consistency of independent sources of data on incidence, prevalence and duration, validates estimates of these parameters. Pooled estimates of the annual incidence rate in women aged 16–24 and 16–44 years for 2001–2005 using all these data were 0·05 [95% credible interval (CrI) 0·035–0·071] and 0·021 (95% CrI 0·015–0·028), respectively. Although, the estimates apply to England, similar methods could be used in other countries. The methods could be extended to dynamic models to synthesize, and assess the consistency of data on contact and transmission rates.
- Subjects :
- Adult
Pathology
medicine.medical_specialty
Adolescent
Epidemiology
Population
Bayesian analysis
Chlamydia trachomatis
medicine.disease_cause
multi-parameter evidence synthesis
Modelling
Credible interval
medicine
Prevalence
Humans
Mass Screening
Chlamydia
education
Mass screening
Estimation
education.field_of_study
business.industry
Incidence (epidemiology)
evidence synthesis
Chlamydia Infections
medicine.disease
Original Papers
3. Good health
Infectious Diseases
England
Relative risk
incidence
Female
business
Demography
Subjects
Details
- Language :
- English
- ISSN :
- 14694409 and 09502688
- Volume :
- 142
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Epidemiology and Infection
- Accession number :
- edsair.doi.dedup.....b7a1eb9123a2914e29006bcc7f9a2a42