Back to Search
Start Over
Insect Sex-Pheromone Signals Mediated by Specific Combinations of Olfactory Receptors
Insect Sex-Pheromone Signals Mediated by Specific Combinations of Olfactory Receptors
- Source :
- Science. 307:1638-1642
- Publication Year :
- 2005
- Publisher :
- American Association for the Advancement of Science (AAAS), 2005.
-
Abstract
- We describe two male-specific olfactory receptors (ORs) in the silk moth, Bombyx mori , that are mutually exclusively expressed in a pair of adjacent pheromone-sensitive neurons of male antennae: One is specifically tuned to bombykol, the sex pheromone, and the other to bombykal, its oxidized form. Both pheromone ORs are coexpressed with an OR from the highly conserved insect OR subfamily. This coexpression promotes the functional expression of pheromone receptors and confers ligand-stimulated nonselective cation channel activity. The same effects were also observed for general ORs. Both odorant and pheromone signaling pathways are mediated by means of a common mechanism in insects.
- Subjects :
- Male
Patch-Clamp Techniques
Molecular Sequence Data
Genes, Insect
Ligands
Receptors, Odorant
Bombykol
Ion Channels
Olfactory Receptor Neurons
Xenopus laevis
chemistry.chemical_compound
Bombyx mori
Cations
medicine
Animals
Sex Attractants
Receptor
In Situ Hybridization
Multidisciplinary
Olfactory receptor
Dose-Response Relationship, Drug
biology
VUAA1
fungi
Sense Organs
Anatomy
Bombyx
biology.organism_classification
Cell biology
Alkadienes
medicine.anatomical_structure
chemistry
Sex pheromone
Odorants
Insect Proteins
Pheromone
Female
Fatty Alcohols
Cation channel activity
Signal Transduction
Subjects
Details
- ISSN :
- 10959203 and 00368075
- Volume :
- 307
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....b80a50427b23c5097858316fa2879cf3
- Full Text :
- https://doi.org/10.1126/science.1106267