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Aging-associated genes and let-7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy
- Publication Year :
- 2019
-
Abstract
- Oculopharyngeal muscular dystrophy (OPMD) is a late-onset muscle disease caused by an abnormal (GCN) triplet expansion within the polyadenylate-binding protein nuclear 1 gene and consequent mRNA pr...
- Subjects :
- 0301 basic medicine
Male
Aging
Oculopharyngeal
Muscle Development
Biochemistry
Myoblasts
0302 clinical medicine
80 and over
Muscular Dystrophy
HMGB1 Protein
PAX7 Transcription Factor
Cell Differentiation
differentiation
Middle Aged
Cell biology
medicine.anatomical_structure
Female
Myogenin
Mitogen-Activated Protein Kinases
Biotechnology
Differentiation, regeneration, skeletal muscle
Adult
Biology
Inclusion Body
Oculopharyngeal muscular dystrophy
03 medical and health sciences
microRNA
Genetics
medicine
Humans
Genetic Predisposition to Disease
regeneration
skeletal muscle
Aged
Aged, 80 and over
Antigens, Neoplasm
Gene Expression Regulation
MicroRNAs
Muscular Dystrophy, Oculopharyngeal
Myositis, Inclusion Body
Antigens
Molecular Biology
Gene
Messenger RNA
Myositis
Regeneration (biology)
Skeletal muscle
medicine.disease
030104 developmental biology
Muscle disease
Neoplasm
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....b83129bca1b4d30939fc9d4f6045e149