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Microbiological Characteristics and Clinical Outcomes of Acinetobacter spp. Endophthalmitis with the First Reported Case of Acinetobacter haemolyticus Endophthalmitis
- Source :
- Seminars in Ophthalmology. 33:477-481
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- Aim To present the microbiological details and clinical outcomes of Acinetobacter spp. endophthalmitis with the first reported case of A. haemolyticus. Methods A retrospective study of microbiologically proven Acinetobacter spp. endophthalmitis was carried out from 2010 to 2015. The data collected included age, type of endophthalmitis, best-corrected visual acuity (BCVA), species involved, and antibiotic susceptibility pattern. The primary outcomes measured were anatomical outcomes in terms of globe integrity and functional outcome as BCVA at last follow-up. Results Eleven patients out of 3004 patients who underwent surgery for endophthalmitis were due to Acinetobacter spp. Seven cases (63.6%) were both smear and culture positive; there were two cases (18%) each of A. haemolyticus and A. baumanii. Four cases (36%) were only culture positive with negative smear. Three cases (27.2%) were polymicrobial. Ten cases (91%) were susceptible to amikacin and nine (82%) to ciprofloxacin. Six (54.5%) were resistant to ceftazidime. Mean logMAR BCVA improved to 1.8 (20/1330) from an initial 2.5 (20/6839). Pthisis bulbi was seen in two cases (18%). Conclusions Even though the outcomes of Acinetobacter spp. endophthalmitis are modest to poor, outcomes following intervention are relatively good for A. haemolyticus. These cases have good susceptibility to amikacin, but are often resistant to ceftazidime.
- Subjects :
- Adult
Male
0301 basic medicine
medicine.medical_specialty
medicine.drug_class
030106 microbiology
Antibiotics
Visual Acuity
Ceftazidime
Microbial Sensitivity Tests
Acinetobacter haemolyticus
Eye Infections, Bacterial
03 medical and health sciences
0302 clinical medicine
Endophthalmitis
Internal medicine
medicine
Humans
Retrospective Studies
Acinetobacter
biology
business.industry
Retrospective cohort study
General Medicine
Middle Aged
biology.organism_classification
medicine.disease
Anti-Bacterial Agents
Surgery
Vitreous Body
Ciprofloxacin
Ophthalmology
Amikacin
030221 ophthalmology & optometry
business
Acinetobacter Infections
medicine.drug
Subjects
Details
- ISSN :
- 17445205 and 08820538
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Seminars in Ophthalmology
- Accession number :
- edsair.doi.dedup.....b835c3dda09da41034cbfa460a17330c