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Logistics and technique for procurement of intestinal, pancreatic, and hepatic grafts from the same donor

Authors :
Thomas E. Starzl
Ernesto P. Molmenti
Juan Madariaga
Javier Bueno
Jorge Reyes
Kareem Abu-Elmagd
George V. Mazariegos
Robert J. Corry
John J. Fung
D Martin
Geoffrey Bond
Source :
Annals of surgery. 232(5)
Publication Year :
2000

Abstract

To assess a technique for simultaneous recovery of the intestine, pancreas, and liver from the same donor.With the more frequent use of pancreatic and intestinal transplantation, a procurement procedure is needed that permits retrieval of both organs as well as the liver from the same cadaveric donor for transplantation to different recipients. It is believed by many procurement officers and surgeons, however, that this objective is not technically feasible.A technique for simultaneous recovery of the intestine, pancreas, and liver was used in 13 multiorgan cadaver donors during a 26-month period, with transplantation of the organs to 33 recipients. The intestine was removed from 11 donors separately and in continuity with the pancreas in the other 2. Six additional pancreases were excised and transplanted separately. Thirteen livers were retrieved, one of which was discarded because of steatorrhea. Ten of the remaining 12 livers were transplanted intact; the other 2 were split in situ and used as reduced-size hepatic allografts in four recipients.None of the 11 intestinal, 6 pancreatic, 2 intestinal-pancreatic, or 14 whole or partial liver allografts sustained serious ischemic injury or were lost as a result of technical complications. One liver recipient died 25 months after surgery of recurrent C virus hepatitis. The other 32 recipients had adequate allograft function with a mean follow-up of 8 months.It was possible using the described technique to retrieve intestine, pancreas, and liver allografts safely from the same donor and to transplant these organs to different recipients.

Details

ISSN :
00034932
Volume :
232
Issue :
5
Database :
OpenAIRE
Journal :
Annals of surgery
Accession number :
edsair.doi.dedup.....b837bbffcd30184e02b05012cd342e36