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Ceiba speciosa (A. St.-Hil.) Seeds Oil: Fatty Acids Profiling by GC-MS and NMR and Bioactivity
- Source :
- Molecules, Molecules, Vol 25, Iss 5, p 1037 (2020), Volume 25, Issue 5
- Publication Year :
- 2020
- Publisher :
- MDPI, 2020.
-
Abstract
- This study aimed to evaluate the chemical composition by gas chromatography-mass spectrometry (GC-MS) and Nuclear Magnetic Resonance (NMR) analyses, the antioxidant activities evaluated by different in vitro assays namely 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2&prime<br />azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), Ferric Reducing Ability Power (FRAP), and &beta<br />carotene bleaching tests, and the inhibitory effects of enzymes linked to obesity (lipase, &alpha<br />amylase, and &alpha<br />glucosidase) of fixed seed oil of Ceiba speciosa (A. St.-Hil.). Fourteen compounds were identified. Linoleic acid (28.22%) was the most abundant followed by palmitic acid (19.56%). Malvalic acid (16.15%), sterculic acid (11.11%), and dihydrosterculic acid (2.74%) were also detected. C. speciosa fixed oil exerted a promising ABTS radicals scavenging activity with an IC50 value of 10.21 &micro<br />g/mL, whereas an IC50 of 77.44 &micro<br />g/mL against DPPH+ radicals was found. C. speciosa fixed oil inhibited lipase with an IC50 value of 127.57 &micro<br />g/mL. The present investigation confirmed the functional properties of C. speciosa fixed oil, and proposes its use as valuable source of bioactive constituents.
- Subjects :
- obesity
Antioxidant
antioxidant
DPPH
Linoleic acid
medicine.medical_treatment
Malvalic acid
Pharmaceutical Science
01 natural sciences
Article
Analytical Chemistry
Palmitic acid
lcsh:QD241-441
chemistry.chemical_compound
0404 agricultural biotechnology
lcsh:Organic chemistry
fixed oil
Drug Discovery
medicine
Settore BIO/15 - Biologia Farmaceutica
Physical and Theoretical Chemistry
Lipase
Chromatography
ABTS
biology
diabetes
Organic Chemistry
04 agricultural and veterinary sciences
Settore CHIM/06 - Chimica Organica
biology.organism_classification
040401 food science
NMR
0104 chemical sciences
010404 medicinal & biomolecular chemistry
chemistry
Chemistry (miscellaneous)
diabete
biology.protein
Molecular Medicine
GC-MS
Ceiba speciosa
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 25
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....b8b2a618956e0d44d7819771cba07aef